Work with the Experts in Biophysics

Check out our new service for
FRAGMENT-BASED DRUG DISCOVERY
and our new product line:
FDA-plate

Our mission is to accelerate your research by developing and applying high-end, scalable assays for

Drug Discovery

Antibody Development

Aptamer Research

Protein Biophysics

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Our Mindset – why you should work with us

Milestone-based projects

Milestones and exit-options give you the full control over your projects.

Clear cost-structure

All costs are known prior to project start. Cancelled milestones are not charged.

Fast turn-around times

The structured project pipeline ensures turn-around times of few working days even for complex screening projects.

Long-standing expertise

2bind is the first CRO certified by NanoTemper for MST and nanoDSF.

Personal project manager

All customer projects are handled by highly skilled, PhD-level biochemists and biophysicists.

Customers from Pharma, Biotech, and Academia

Completed contract research projects

Years of experience with MST and nanoDSF

Protein, DNA, RNA targets analyzed

State-of-the-art Biophysics

Our state-of-the-art portfolio of biophysical technologies enables us to provide you with a complete and comprehensive picture of your specific question: From affinity and stability to kinetics and thermodynamics.

KD | EC50 | Tm | ΔTm | Tagg | ΔTagg | kon | koff | n | ΔH | ΔG | ΔS

MST

  • Steady-state affinity
  • Ligand binding
  • Screening
  • Proteins, DNA, RNA
  • Bioliquids

nanoDSF

  • Protein stability
  • Protein unfolding
  • Protein aggregation
  • Ligand binding
  • Screening
  • Bioliquids

BLI

  • Kinetics
  • Ligand binding
  • Antibody development
  • Off-rate ranking
  • Bioliquids

ITC

  • Thermodynamics
  • Stoichiometry
  • Ligand binding

Clients & Partners

We used the services of 2bind several times, including MST, BLI and nanoDSF and were always happy with the excellent service and result quality.

Philipp Richle  CDR-Life AG
Philipp Richle

We are impressed with the rapid turnaround time and excellent service, as well the high quality data generated at 2bind.

Brian Hamman, Director of Biophysics  Arvinas, Inc.
Brian Hamman, Director of Biophysics

The [2bind] assay development was well-planned, careful and methodical. Progress reports were frequent, very clear and meticulously prepared. Their science and professionalism are impeccable – working with 2bind is like having expert biophysicists in the lab next door!

Chris Lepre, PhD, Biochemistry, Biophysics and Structural Biology  Relay Therapeutics, Inc.
Chris Lepre, PhD, Biochemistry, Biophysics and Structural Biology

The MST experts at 2bind were successfull in setting up various binding assays, stoichiometry assays, and competition assays and helped us to drive our science. We are very satisfied with the low sample consumption and the fast turnaround time.

Mads Nøregaard-Madsen, Chief Innovation & Information Officer  Nuevolution
Mads Nøregaard-Madsen, Chief Innovation & Information Officer

During several years we have had excellent experience working with 2bind. They have always provided us with the highest-quality services. Quick responsiveness of 2bind’s team has helped us to accelerate projects.

Dmitry Shishov  Gero
Dmitry Shishov

We have enjoyed the quality of service of 2bind coupled to a great flexibility. 2bind’s technology allowed us to quickly assess target validation with dozens of proteins and helped us advance quickly on the subject.

Philippe Verwaerde, President and CSO  AlzProtect
Philippe Verwaerde, President and CSO

We have been using NanoTemper devices for over eight years and have established a close and very productive relationship together. 2bind has the highest density of NanoTemper devices in one lab world-wide.

Assay.Works is our go-to partner for all biochemical and cell-based assay development and screening requirements. We partner also in the area of ligand compound and bioactive tool compound libraries.

Media and Ressources

We are sure there is a service for your exact needs!
Have a look at the 2bind Application Notes and peer-reviewed publications to see what we can do!

Contact Specialist