Science and Publications

Science & Publications

Highlights

Structural basis of CDNF interaction with the UPR regulator GRP78

ARMADILLO REPEAT ONLY proteins confine Rho GTPase signalling to polar growth sites

QTY code designed thermostable and water-soluble chimeric chemokine receptors with tunable ligand affinity

QTY code enables design of detergent-free chemokine receptors that retain ligand-binding activities.

The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors.

All Publications

SEC-SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded-Over Conformations

Structural basis of CDNF interaction with the UPR regulator GRP78

Enhancement of complement-dependent cytotoxicity by linking factor-H derived short consensus repeats 19-20 to CD20 antibodies

Supramolecular Complex of Cucurbit[7]uril with Diketopyrrolopyrole Dye: Fluorescence Boost, Biolabeling and Optical Microscopy

Balancing the Affinity and Tumor Cell Binding of a Two-in-One Antibody Simultaneously Targeting EGFR and PD-L1

Biochemical and cellular insights into the Baz2B protein, a non-catalytic subunit of the chromatin remodeling complex

​Impact of single mutations on binding kinetics of triplex forming oligos revealed by fluorescence proximity sensing in heliX® biosensor

Non-full-length Water-Soluble CXCR4-QTY and CCR5-QTY Chemokine Receptors: Implication for Overlooked Truncated but Functional Membrane Receptors

ARMADILLO REPEAT ONLY proteins confine Rho GTPase signalling to polar growth sites

Identifying Novel Targets by using Drug-binding Site Signature: A Case Study of Kinase Inhibitors

QTY code designed thermostable and water-soluble chimeric chemokine receptors with tunable ligand affinity

Biophysical Characterization of Aptamer-Target Interactions

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors. 

Bactericidal/permeability-increasing protein is an enhancer of bacterial lipoprotein recognition.

QTY code enables design of detergent-free chemokine receptors that retain ligand-binding activities.

ALY RNA-Binding Proteins Are Required for Nucleocytosolic mRNA Transport and Modulate Plant Growth and Development

MicroScale Thermophoresis as a Tool to Study Protein-peptide Interactions in the Context of Large Eukaryotic Protein Complexes.

MicroScale Thermophoresis: A Rapid and Precise Method to Quantify Protein–Nucleic Acid Interactions in Solution.

The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences.

Aptatope mapping of the binding site of a progesterone aptamer on the steroid ring structure.

The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors.

The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors.

The characterization and validation of 17β-estradiol binding aptamers.

The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis.

Aptamer Binding Studies Using MicroScale Thermophoresis.

Studying small molecule–aptamer interactions using MicroScale Thermophoresis (MST).

Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.

ß-Conglutin dual aptamers binding distinct aptatopes.

Review: Studying epigenetic interactions using MicroScale Thermophoresis (MST).

In vitro Selection and Interaction Studies of a DNA Aptamer Targeting Protein A.

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression.

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.

Emerging company profile – 2bind GmbH.

Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1.

Arabidopsis DEAD-Box RNA Helicase UAP56 Interacts with Both RNA and DNA as well as with mRNA Export Factors.

Large-scale organization of ribosomal DNA chromatin is regulated by Tip5.

Df31 protein and snoRNAs maintain accessible higher-order structures of chromatin.

Microscale thermophoresis as a sensitive method to quantify protein: nucleic acid interactions in solution.

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