Publications

Highlights

PNAS | Nov 2019

QTY code designed thermostable and water-soluble chimeric chemokine receptors with tunable ligand affinity

Advances in Biochemical Engineering | Aug 2019

Biophysical Characterization of Aptamer-Target Interactions

PNAS | Aug 2018

QTY code enables design of detergent-free chemokine receptors that retain ligand-binding activities.

Plant Cell | apr 2017 | open access

The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors.

All Publications

BiorXiv | Dec 2019

Identifying Novel Targets by using Drug-binding Site Signature: A Case Study of Kinase Inhibitors

PNAS | Nov 2019

QTY code designed thermostable and water-soluble chimeric chemokine receptors with tunable ligand affinity

Advances in Biochemical Engineering | Aug 2019

Biophysical Characterization of Aptamer-Target Interactions

Cell Death & Disease | Apr 2019 | open access

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors. 

Frontiers in Immunology | Dez 2018 | open access

Bactericidal/permeability-increasing protein is an enhancer of bacterial lipoprotein recognition.

PNAS | Aug 2018

QTY code enables design of detergent-free chemokine receptors that retain ligand-binding activities.

Plant Physiology | May 2018 | open access

ALY RNA-Binding Proteins Are Required for Nucleocytosolic mRNA Transport and Modulate Plant Growth and Development

Bio-protocol | nov 2017 | open access

MicroScale Thermophoresis as a Tool to Study Protein-peptide Interactions in the Context of Large Eukaryotic Protein Complexes.

Methods in Molecular Biology | sep 2017

MicroScale Thermophoresis: A Rapid and Precise Method to Quantify Protein–Nucleic Acid Interactions in Solution.

PLoS One | jun 2017 | open access

The monoclonal S9.6 antibody exhibits highly variable binding affinities towards different R-loop sequences.

Analytical Biochemistry | may 2017

Aptatope mapping of the binding site of a progesterone aptamer on the steroid ring structure.

Plant Cell | apr 2017 | open access

The Composition of the Arabidopsis RNA Polymerase II Transcript Elongation Complex Reveals the Interplay between Elongation and mRNA Processing Factors.

The Journal of Steroid Biochemistry and Molecular Biology | mar 2017

The characterization and validation of 17β-estradiol binding aptamers.

Plant Molecular Biology | feb 2017

The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.

Journal of Visualized Experiments | jan 2017 | open access

Mapping the Binding Site of an Aptamer on ATP Using MicroScale Thermophoresis.

Springer Protocols, Methods in Molecular Biology | sep 2016

Aptamer Binding Studies Using MicroScale Thermophoresis.

Methods | mar 2016

Studying small molecule–aptamer interactions using MicroScale Thermophoresis (MST).

Bioanalytical Chemistry | nov 2015 | open access

ß-Conglutin dual aptamers binding distinct aptatopes.

Human Molecular Genetics | nov 2015 | open access

Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.

AIMS Biophysics | aug 2015 | open access

Review: Studying epigenetic interactions using MicroScale Thermophoresis (MST).

PLoS One | jul 2015 | open access

In vitro Selection and Interaction Studies of a DNA Aptamer Targeting Protein A.

Cell | jun 2015 | open access

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression.

Genes and Development | apr 2014 | open access

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.

BioCentury | feb 2014

Emerging company profile – 2bind GmbH.

Nucleic Acids Research | jul 2013 | open access

Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1.

Nucleic Acids Research | mar 2013 | open access

Large-scale organization of ribosomal DNA chromatin is regulated by Tip5.

PLoS One | mar 2013 | open access

Arabidopsis DEAD-Box RNA Helicase UAP56 Interacts with Both RNA and DNA as well as with mRNA Export Factors.

Molecular Cell | nov 2012 | open access

Df31 protein and snoRNAs maintain accessible higher-order structures of chromatin.

Methods in Molecular Biology | nov 2011

Microscale thermophoresis as a sensitive method to quantify protein: nucleic acid interactions in solution.
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